مجله دانشکده پزشکی زابل
سال ششم شماره 1 (پیاپی 18، بهار 1402)

End Stage Renal Disease(ESRD) can cause lung dysfunction throughseveral mechanisms. The aim of this study was to determine the effect of hemodialysis on shortness of breath and Peakexpiratory flow(PEF) at the onset and after dialysis in hemodialysis and ESRD patients.

In this cross-sectional study, 209 patients with ESRD who had been on dialysis for at least 3 months were evaluated. Shortness of breath and PEFwere measured before and after dialysis. Data were analyzed with asignificance level of less than 0.05.

According to the results, 53.1% of patients were male and 46.9% were female. The mean (SD) age of patients was 57.8 (14.3) years and the duration of dialysis was 37.7 (33.6) months. The mean (SD) PEFbefore dialysis was 267.9 ±106.3 which increased to 284.6 (113.3) liters per minute after dialysis (p value= 0.001). Patients with High-flux filtration had a higher mean PEFbefore and after dialysis and less dyspnea after dialysis. Spearman correlation showed a positive correlation between hemodialysis duration and PEF(r = 0.2, p value= 0.011) and positive correlation between the number of weekly hemodialysis sessions (r = 0.2, p value= 0.020) andThere was a negativecorrelationbetween the PEFwith patients' age. (r = -0.2, p value= 0.006).

The results of this study showed thatPEFafter dialysis increases in ESRDpatients, which in patients using high-flux filters, in addition to increasing the PEF, decreases the severity of shortness of breath.

The policies established to control the corona virus can cause anxiety of the Coronavirus (COVID-19). Corona anxiety can affect all levels of individualslives. The purpose of this research is to investigate the role of Corona anxiety on marital conflicts and psychological well-being of couples in Mashhad.

This is a cross-sectional correlationalstudy. The statistical population of the research included all married couples living inMashhad city, based on Green's rule (1991), 150 people were selected by available sampling method. In this research, Alipour et al.'s Corona Anxiety Questionnaire (2018), Sanai Zaker's Marital Conflicts Questionnaire (2008), and Rief's Psychological Well-Being Questionnaire (1989) were used for data collection. Data analysis was conducted using Pearson correlation and regression analysis.

The results of Pearson's correlation analysis revealeda positive and significant relationship between Corona anxiety and marital conflicts;additionalythere wasa negative and significant relationship between Corona anxiety and psychological well-being.regressionanalysisshowed that Corona anxiety can significantly predict 11.1% variance relatedto marital conflicts in Mashhad couples. Also, the regression results showed that Corona anxiety can significantly predict 4% variancerelated to psychological well-being in Mashhad couples.

The findings of this research indicatethat Corona anxiety plays an important role in predicting marital conflicts and psychological well-being.

Pilonidal sinus is an inflammatory disease that occurs acutely and chronically in the sacrococcygealregion. The pathogenesis of the disease is not precisely known and the treatment of choice is surgery; which can be done in different ways. In the present study, the results of two open and semi-closed surgical methods were investigated and compared.

A total of 150 patients with pilonidal sinus referred to Bandar Abbas Shahid Mohammadi Hospital who were candidates for surgery were randomly divided into two equal groups including group 1 with open surgery and group 2 with semi-closed surgery. P value < 0.05 was considered significant.

In the current study 150 patients were analyzed which divided into two groups consisting of 75 patients in each one of them and one group (group 1) and another group (group 2) were treated with open and semi-closure techniques, respectively. In group one were 52 male and 23 female patients, in group two 53 male and 22 female, group one and two average age were 26.17 ± 8.4 and 25.81 ± 8, respectively.

Overall results of the study demonstrate that there is no significant difference between the two procedures on recurrence and postoperative infection perspectives and also there was a significant privilege in semi-closure technique on hospitalization time, healing period, avoidance of work perspectives. And also this study demonstrated there is no significant relationship between demographic features and side effect incidents.

Systemic lupus erythematosus (SLE) as an inflammatory autoimmune disease, originates from the production of autoantibodies against several cellular components, especially nuclear components such as DNA. Prolactin consists of 199 amino acids and due to the structural similarity with cytokines, this polypeptide has the ability to modulate the immune system, which is characterized by the observation of hyperprolactinemia in autoimmune disorders. The rs1341239 polymorphism of the prolactin gene is associated with several autoimmune diseases. The purpose of this study is to investigate the relationship between this polymorphism and prolactin serum level in SLE patients in a population from Iran.

Genotype analysis of prolactin rs1341239 gene polymorphism was performed using blood samples of 90 SLE patients as patients’ group and 90 control samples as the control group through RFLP-PCR method. Also, serum prolactin concentration was measured using ELISA method.

Our results showed a significantly higher serum level of prolactin in patients group than in the control group. There was no significant difference in alleles and genotypes frequencies of rs1341239 polymorphism in patients group compared to the control group. However, a significant correlation was found between the frequency of GG genotype and the reduction of platelets in the blood of patients group.

Our results did not show a significant difference in the frequency of prolactin rs1341239 gene polymorphism in patients and control groups, while we observed the relationship between this polymorphism and platelet count in patients group.

Acute respiratory infections are caused by a wide range of viruses. Respiratory spread is the main process of disease transmission. We evaluated neutrophil-to-lymphocyte ratio(NLR), platelet-to-lymphocyte ratio (PLR) and monocyte-lymphocyte ratio (MLR) indices.

This descriptive-analytical study was conducted on patients-files between September 2019 and March 2021. 102 patients were evaluated. 26 men and 30 women were included in the acute coronary group, 16 men and 30 women were included in the non-acute coronary group.

The mean age of women (53.0 ± 1.9) was higher than that of men (50.2 ± 2.02) in the acute coronary group. The mean NLR index in coronary men (65 ± 1.47) was higher than non-acute coronary men (54 ± 1.76). It was also higher in coronary women (54 ± 2.78 ± 10) than non-acute coronary women (24 ± 1.97) (p value > 0.05). PLR index of coronary men (85 ± 43.15) was lower than the non-acute men (48.3 ± 48.15). But this index was lower in coronary women (36.3 ± 5.22) than the non-acute women (2.4 ± 2.25) (p value > 0.05). The mean of MLR index in coronary men (0.16 ± 0.025) was less than the coronary women (0.03 ± 0.26) (p value > 0.05). The mean MLR index in non-acute men (0.04 ± 0.22) was lower than the non-acute women (0.02 ± 0.23) (p value > 0.05). The mean MLR in the coronary men (0.025 ± 0.16) was lower than non-acute men (0.04 ± 0.22). This index was higher in coronary women (0.03 ± 0.26) than the non-acut women (0.02 ± 0.23) (p value > 0.05).

The changes in NLR, PLR and MLR indices were in accordance with global studies but were not significant. It may be due to immune responses of patients and laboratory errors (sampling and performing techniques)

Spiritual care is an intervention based on the client's potential power of faith and spirituality, in order to empower him to use spiritual resources, in order to deal with critical situations, including pregnancy. Physical and mental changes during pregnancy make women mentally vulnerable. The purpose of this study is to review the researches done about the effect of spiritual care on pregnancystress and anxiety.

In thisstudy, to find articles,search databases, Google Scholar; Iran Medex; Magiran; SID and using a combination of Persian keywords Spiritual care, Spirituality, Pregnant women, Childbirthand their English equivalent in databases, Embase, Web of Science, PubMed, Scopus without time limit were searched. From a total of 28 articles obtained after careful review in terms of providing duplicate results, 15 articles were selected and finally 7 articles in terms of inclusion andexclusion criteria in this study were included and reviewed.

In general, it can be said that the number of studies conducted in recent years focusing on the effect of spirituality on pregnancy and childbirth is limited. The results of studies have shown that spiritual care can reduce stress, anxiety, depression and even increase the quality of life of pregnant women.

Spirituality can help people to evaluate negative events in a different way, this first creates a sense of control over oneself and the environment, and then reduces anxiety, stress and increases the quality of life.